Learning Objectives; Keywords; Pre-Lab Reading; Pre-Lab Quiz; Slides; Virtual Microscope; Pathology; Quiz ; Immune System Lab. Although in elderly patients atrophic changes can be present, in general it is only above 80 years of age that the composition of the spleen is severely altered and the weight of the spleen diminished. The red pulp In this section, we describe the efficient blood-filtering system of the spleen and its importance for iron recycling by splenic macrophages of the red pulp. No public clipboards found for this slide. The spleen is the largest accumulation of lymphoid tissue in the body. Looks like you’ve clipped this slide to already. Spleen histology slide (labeled) The spleen is a fist sized organ located in the left upper quadrant of the abdomen. Tissues Cells work ... framwork in soft organs (i.e. After antigen presentation and T-cell help, activatedB-cells set up germinal centers in secondary follicles Secondary follicle germinal centers • Arise when B-lymphocytes are presented with appropriate antigen, receive T-cell help, and then begin proliferating as lymphoblasts • Lymphoblasts differentiate into plasma cells or memory cells; aberrant lymphoblasts undergo apoptosis. FIGURES 3. I have tried to explain the identification points of the spleen. Presentation Summary : Describe the gross anatomy and histology of the following lymphoidorgans: Spleen, tonsils, thymus, lymph nodes and mucosa associated. We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. The spleen reaches peak development at puberty, in rats, followed by gradual involution (Losco, 1992). Liver Histology Groby Bio Page 174952 PPT. In this video, I have tried to narrate the salient features of histology of the spleen. Spleen pathology Introduction Open surgery for splenectomy is performed with diminishing frequency and pathology of this organ remains a poorly un-derstood topic. The lesion is typically a solitary, well demar-cated nodule protruding from the spleen (Figure 35). The spleen contains hematopoietic and lymphoid elements, is a primary site of extramedullary hematopoiesis, and removes degenerate and aged red blood cells as well as particulate materials and circulating bacteria from the blood supply. See our User Agreement and Privacy Policy. • Pleural cavity separates spleen and diaphragm from the rib. This diagrammatic representation of the spleen, should help you understand where red and white pulp come from. 3. Spleen - Congestive splenomegaly. 4. If you continue browsing the site, you agree to the use of cookies on this website. • 2nd lymphoid organ ,Oval in shape, 7 -14cm in length and 150 -200 grams in weight. These functions are carried out by the 2 main compartments of the spleen, the wh … Normal structure, function, and histology of the spleen Toxicol Pathol. & 4.—Spleen from a F344 rat on 50% caloric restriction for two weeks. Spleen 1. Anatomy Develops from mesenchymal cells in the dorsal mesogastrium during the fifth week of gestation. • Has Diaphragmatic ,visceral and colic surface and anterior ,posterior and inferior border. rodent spleens are schematically illustrated in FIG.
What is a SPLEEN?
3. If your are looking for the best guide to learn histological features of spleen structure then you may continue this article. The spleen is the largest secondary immune organ in the body and is responsible for initiating immune reactions to blood-borne antigens and for filtering the blood of foreign material and old or damaged red blood cells. 1b. Presentation Summary : Liver histology. Spleen This is a low power view of the spleen. Now customize the name of a clipboard to store your clips. The spleen is surrounded by a capsule of dense connective tissue from which emerge trabeculae, which divide the parenchyma, or splenic pulp, into incomplete compartments.Large trabeculae originate at the hilum, on the medial surface of the spleen; these trabeculae carry nerves, arteries and veins. In 50 cases of sudden infant death cervical, paratracheal and lung hilar lymph nodes, the thymus and the spleen were investigated by histology and immunohistochemistry (CD 20, 21, 45RO). Guided needle core biopsy is used increasingly to sample solid lesions within the spleen and, for a variety of pathologies, laparoscopic splenectomy is now the surgical method of choice. Normal Structure, Function, and Histology of the Spleen MARK F. C ESTA Integrated Laboratory Systems, Inc., Durham, North Carolina 27713, USA ABSTRACT The spleen is the largest secondary immune organ in the body and is responsible for initiating immune reactions to blood-borne antigens and for filtering the blood of foreign material and old or damaged red blood cells. Histology. Lymphocytes All lymphocytes originate in the bone marrow. Histology Of The Spleen Histologie Van Die Milt 451329 PPT Presentation Summary : Nose, olfactory region and the sinuses (L1) 2012 Nose Nose wings Olfactory mucosa nasal conchae Respiratory mucosa Nasal ala lamina propria hyaline Slide List. (This topic is beyond the scope of the present review.) We have 600 guests and no members online If you continue browsing the site, you agree to the use of cookies on this website. It is the largest lymphoid organ and thus the largest filter of blood in the human body. 1. Large aggregation of lymphocytes form lymphoid organs ( thymus, spleen, lymph nodes and tonsils). The spleen is located in the left upper quadrant region of the abdomen. In dogs, the spleen increases in weight during the first 6 months of life (HoganEsch and Hahn, 2001). Numerous references discuss the effects of aging on lymphocyte function and changes in the distribution of lymphocyte subsets. See our Privacy Policy and User Agreement for details. 12 … Starter: Review your FLIP learning, discuss what you learnt with the person next to … Now customize the name of a clipboard to store your clips. Lymph nodes. (80 -300 gr). Prac - Looking at liver slides. Connective Tissue Proper - Classifications Loose Connective Tissue Areolar Reticular Adipose Dense Connective Tissue Regular Irregular Elastic. 4. You can change your ad preferences anytime. Histology Of The Spleen Histologie Van Die Milt 451329 PPT Presentation Summary : Nose, olfactory region and the sinuses (L1) 2012 Nose Nose wings Olfactory mucosa nasal conchae Respiratory mucosa Nasal ala lamina propria hyaline Theperitoneum covering thespleen, except in the hilum. Looks like you’ve clipped this slide to already. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Histology of spleen By; Dr Talat Saeed Learning objectives At the end of the lecture student should Welcome back to anatomy learner and thanks for getting into this article – spleen histology red and white pulp with slide images and labeled diagram. Spleen & liver) Ground substance: Along with fibers, fills the extracellular space Ground substance helps determine functionality of tissue. You can change your ad preferences anytime.
It’s part of the circulatory system.
It acts as a filter for blood.
Not vital for human survival. 3. Note also the marginal zone and recall that this is where most antigen presentation occurs in the spleen. On the outer edge, note the presence of a capsule from which short trabeculae (containing a trabecular artery and trabecular vein) extend into the parenchyma. • Lies just beneath the left half of the diaphragm close to 9 ,10 and 11 ribs and on the left side of abdomen. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Histology @ Yale. influence the histology of the spleen such as the well documented 1~ pre- and postnatal development of the white pulp. 7cm 150 gr. Title: Histology of the spleen Histologie van die milt Author: Carel Pretorius Last modified by: Created Date – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - … Histology @ Yale. If you continue browsing the site, you agree to the use of cookies on this website. In this video, you will learn and study the Histology of the Spleen and functions of B cells and T cells. Lymphoid Tissue Quiz Including Answers. Look at slide 141 and observe the histology of thymic involution, which is basically a replacement of lymphatic tissue by fat. Spleen is an important internal organ that is on average not larger than the size of a fist. Spleen ... | PowerPoint PPT presentation | free to view . Clipping is a handy way to collect important slides you want to go back to later. Therefore, it is necessary that a system be implemented to prevent foreign organisms from invading the body and disrupting this highly regulated environment. Histology of lymphatic system The lymphoid system includes lymphatic vessels and lymphoid organs. Clipping is a handy way to collect important slides you want to go back to later. UMich Slide 147B: Spleen, human, H&E [DigitalScope] This slide provides another view of a human spleen with its fibromuscular capsule (and even an intact mesothelium in some places), trabecula, red pulp, and white pulp. … If you continue browsing the site, you agree to the use of cookies on this website. Lesions of this important component of the immune system may center on the red pulp, the white pulp or involve both compartments The spleen … In spleen histology, you will find the two important structures – connective tisuue framework and parenchyma. No public clipboards found for this slide. FIGURES 5. B6C3F1 mouse, female, 20 weeks old (left) and F344/N rat, male, 12 weeks old. Lymphatic vessels are closely associated with the blood vascular system, and they drain into the systemic circulation. Learning Objectives. Click here to submit questions or comments about this site. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. (right). See our Privacy Policy and User Agreement for details. Thymus (histological slide) The human body operates under strict homeostatic rules that must be maintained in order to support the physiological activity of the multiple organ systems working together. The spleen removes old red blood cells (erythrocytes) from the blood supply. Spleen. Thymus. Universidad de Guadalajara Centro Universitario Ciencias de la Salud SpleenGiovanna Lazcano Sherman Dr. Héctor Manuel Virgen Ayala November 2011 Dr. Benjamín Robles Mariscal 2. See our User Agreement and Privacy Policy. The spleen has a unique location, embryological development and histological structure that differs significantly from other lymphoid organs. In contrast to the other organs we have seen so far, the spleen is not arranged into cortex and medulla. Spleen anatomy 1. We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. Abhishek jha 2. Universidad de Guadalajara Centro Universitario Ciencias de la Salud SpleenGiovanna Lazcano Sherman Dr. Héctor Manuel Virgen Ayala November 2011 Dr. Benjamín Robles Mariscal. & 6.—Spleen from an ad libitum control on the same study as Figures 3 and 4. et al., 1990). They … See Elsevier's new video about their Clinic Review Articles further down on this page or click here. View histology of spleen ,by dr Talat.pptx from BIOLOGY 1 at Karachi Medical & Dental College.
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